Neurofibromatosis (NF) is a multisystem genetic disorder that commonly is associated with cutaneous, neurologic, and orthopedic manifestations. NF is defined by tumors, called neurofibromas that grow along nerves in the body or on or under the skin. As the tumors increase in size, they can press on vital areas of the body, causing problems in the way the body functions. NF can cause growth of non-cancerous tumors on nerve tissue, producing skin and bone abnormalities.

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